405€ Find Cheap Flights from Frankfurt am Main to South America – Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Frankfurt am Main to South America departing on 05.09.. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Flight Deals

Best South America Flight Deals from Frankfurt am Main

Cheapest return prices found by our users on KAYAK in the last 72 hours
Lima
Lima2 stops1.012 €
Buenos Aires
Buenos Aires2 stops859 €
Rio de Janeiro
Rio de Janeiro2 stops738 €
Asuncion
Asuncion2 stops871 €
Lima
Lima2 stops1.012 €
Buenos Aires
Buenos Aires2 stops859 €
Rio de Janeiro
Rio de Janeiro2 stops738 €
Asuncion
Asuncion2 stops871 €

Cheap Flights from Frankfurt am Main to South America

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for return flights from Frankfurt am Main to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent return flight deals from Frankfurt am Main to South America

Mon, 2. Nov - Mon, 16. Nov
Air Europa Logo
10:45 - 19:50
FRA
-
MDE
15h 05m
1 stop
Air Europa Logo
21:50 - 17:50
MDE
-
FRA
14h 00m
1 stop
727 €Air Europa
Wed, 11. Nov - Thu, 3. Dec
Delta Logo
9:50 - 9:50
FRA
-
GIG
28h 00m
2 stops
Delta Logo
22:55 - 8:40
GIG
-
FRA
29h 45m
2 stops
738 €Delta
Tue, 10. Nov - Tue, 24. Nov
Air Canada Logo
9:45 - 9:00
FRA
-
GRU
27h 15m
1 stop
Air Canada Logo
21:30 - 7:25
GRU
-
FRA
29h 55m
2 stops
779 €Air Canada
Tue, 1. Sep - Wed, 30. Sep
Air Canada Logo
9:55 - 9:50
FRA
-
GRU
28h 55m
1 stop
Air Canada Logo
21:35 - 6:00
GRU
-
FRA
27h 25m
2 stops
780 €Air Canada
Thu, 5. Nov - Sun, 8. Nov
TAP AIR PORTUGAL Logo
17:45 - 6:50
FRA
-
GRU
17h 05m
1 stop
TAP AIR PORTUGAL Logo
1:30 - 22:40
GRU
-
FRA
17h 10m
1 stop
786 €TAP AIR PORTUGAL
Sat, 7. Nov - Sun, 29. Nov
TAP AIR PORTUGAL Logo
6:00 - 19:55
FRA
-
GRU
17h 55m
1 stop
TAP AIR PORTUGAL Logo
16:20 - 12:30
GRU
-
FRA
16h 10m
1 stop
787 €TAP AIR PORTUGAL
Mon, 9. Nov - Thu, 26. Nov
LATAM Airlines Logo
20:50 - 13:30
FRA
-
SDU
20h 40m
2 stops
LATAM Airlines Logo
14:15 - 14:55
SDU
-
FRA
20h 40m
2 stops
816 €LATAM Airlines
Mon, 9. Nov - Sat, 28. Nov
LATAM Airlines Logo
20:50 - 13:10
FRA
-
SDU
20h 20m
1 stop
LATAM Airlines Logo
20:20 - 14:55
SDU
-
FRA
38h 35m
2 stops
817 €LATAM Airlines
Tue, 1. Sep - Tue, 29. Sep
Air France Logo
12:10 - 20:55
FRA
-
CGH
37h 45m
2 stops
Air France Logo
11:55 - 22:05
CGH
-
FRA
29h 10m
2 stops
908 €Air France
Mon, 7. Sep - Sun, 20. Sep
Air France Logo
7:05 - 20:55
FRA
-
CGH
18h 50m
2 stops
Air France Logo
11:50 - 17:45
CGH
-
FRA
24h 55m
2 stops
932 €Air France
Booking Insights

KAYAK's insights & trends for Frankfurt am Main to South America flights

Get data-powered insights and trends into flights from Frankfurt am Main to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Frankfurt am Main to South America flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to South America from Frankfurt am Main found in the last 72 hours was to Sao Paulo, at 788 € return. The most popular route is from Frankfurt am Main Airport (FRA) to Sao Paulo Guarulhos Intl Airport (GRU), and the cheapest round-trip airline ticket found on this route in the last 7 days was 788 €.

What is the cheapest time of day to fly to South America?

The average price for all round-trip flights from Frankfurt am Main to South America depending on the time of departure, clicked by users on KAYAK in the last 2 weeks.

The cheapest time of day to fly to South America is generally in the afternoon, when retur flights cost 981 € on average. The most expensive time of day to fly to South America is generally in the afternoon, which is peak travel time and where the average cost of a ticket is 981 €.

What is the cheapest month to fly from Frankfurt am Main to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Frankfurt am Main to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Frankfurt am Main to South America is May, when tickets cost 883 € (return) on average. On the other hand, the most expensive months are July and December, when the average cost of return tickets is 1.315 € and 1.292 € respectively.

What’s the cheapest day of the week to fly from Frankfurt am Main to South America?

The average price of all round-trip flights from Frankfurt am Main to South America clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Frankfurt am Main to South America, look for departures on Wednesdays and avoid leaving on a Sunday, as it's usually the priciest day. When flying back from South America, Tuesday is the cheapest day to fly and Friday is the most expensive.

How far in advance should I book a flight from Frankfurt am Main to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Frankfurt am Main to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below-average price on a flight from Frankfurt am Main to South America, you should book around 4 weeks before departure, which saves you about 10% compared to booking last-minute. For the absolute cheapest price, our data suggests you should book 13 weeks before departure.

Good to know - Cheap tickets from Frankfurt am Main to South America

Cheapest flight405 €
Flight from Frankfurt am Main to Medellín

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Frankfurt am Main to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Frankfurt am Main to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Frankfurt am Main to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Frankfurt am Main to South America is likely to change within 7 days, so travellers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Frankfurt am Main to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional return ticket. You could then fly from Frankfurt am Main to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Frankfurt am Main to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Frankfurt am Main to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines flying from Frankfurt am Main to South America

 
Need help choosing which airline to fly with from Frankfurt am Main to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7,4
LATAM AirlinesOverall score based on 1940 reviews
7,0Entertainment
8,0Crew
7,3Comfort
7,5Boarding
6,7Food
Airline reviews

In flight from Miami to Anchorage, we were all on board ready to take off. Pilot decided to take on more fuel causing a delay. Once fueled, the pilot came back over the radio stating more delay due to VIP. These delays caused me to miss my connecting flight. I went to the Alaska Air counter for information. They flat out stated that it was ATCs fault that I missed my flight and booked me a flight the next day about 1300 . I believe if we had the fuel prior to getting on board we would not of been delayed and I would have taken off on time. Pilot was taken out of the equation. I think they should’ve taken responsibility for their pilots decision to top off his aircraft instead of waiting til the last moment. Enough said…

2,0 MediocreAnonymous, May 2026
LIM - MIA
Read more LATAM Airlines reviews

In flight from Miami to Anchorage, we were all on board ready to take off. Pilot decided to take on more fuel causing a delay. Once fueled, the pilot came back over the radio stating more delay due to VIP. These delays caused me to miss my connecting flight. I went to the Alaska Air counter for information. They flat out stated that it was ATCs fault that I missed my flight and booked me a flight the next day about 1300 . I believe if we had the fuel prior to getting on board we would not of been delayed and I would have taken off on time. Pilot was taken out of the equation. I think they should’ve taken responsibility for their pilots decision to top off his aircraft instead of waiting til the last moment. Enough said…

We liked the way we were treated by the sraff at lima airport counter and the the flight attendants. We did not like the fact that the kiosks at airport rebooted after we entered our information and then told us that there was an issueand we needed to go to the counter. Such a waste of time for a group of 6. Once we got our boarding passes there was no assigned gate so we did not know where to go.

Nothing I like, I missed this connection b/c of an earlier flight delay. I had to stay one more night and I paid out my own pocket. LATAM failed to send me to a safe and decent hotel.

It was delayed for 2 hours. Then when we arrived they took us on a very uncomfortable bus and left us there. The bus driver wouldn't let us out because no one from Latam was there. Everything was disaster.

LATAM is a great airline who takes care of there guests. They consistently walk around and see if you need water in addition to taking care of all the passengers. The chicken in process is really easy and I’m always offered a chance for an upgrade which I appreciate.

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

LATAM’s crews are fine, but God help you if you need any customer service. Their app and website never work, with error after error. Trying to solve anything over the phone is painful, and lastly, the boarding pass LATAM gave me to board the flight with Delta was invalid and I had to purchase an emergency one-way ticket at the last minute to get home.

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Good flight, boarding ok and crew very nice. Flight was not full so I was able to be very comfortable. Blanket and pillow provided with was good as it was very cold during the flight . Food was very good(small snack sandwich and an excellent piece of orange cake). Overall good flight, no complaints.

The way the Pilot made all announcements, specially the way he congratulated the entire crew as the best team ever, making a comment that due to them they were able to shorter the delay to the destination. Amazing flight .

There were no delays. I almost lost my connection because of the new EES system

Flight attendants in business class were rather indifferent While in second leg operated by Portugalia TAP subsidiary were outstanfy

Chaotic boarding with no announcements. Carry on luggage needs to be checked. Bare minimum zero frill flights. Not a whole lot of anything positive to be said .

The chicken was so dry it was impossible to eat. No substitute was offered. The port to charge my phone was broken and all I got was a shrug from the crew. The entertainment system was glitchy and subtitles didn’t load. Crew seemed fully uninterested and unfriendly.

They left our luggage uncovered on tarmac in pouring rain during an hour delay of departure! At our final destination, we found ALL OF OUR CLOTHES/SHOES soaked all the way through!! Our 1st connection plane was a great business class accommodation but only 50 minutes long. Our 2nd connection from Lisbon (another delay with luggage uncovered on tarmac) had only the extra legroom and mediocre food in business class - no entertainment and no extra comfort seating. Will not use TAP Air Portugal again!

Horrible experience at tbe check in ladie she was very racist ,she doesn't speak portuguese too and forced me to check in my carrion bag and I saw everyone with carrion bag inside anda lot of space ,she was rude unprofessional

The plane was small and one felt the turbulence much more. The lines to get through immigration were insanely long.

Bad. They gave me a voucher for food to use at the airport but didn’t have time since I had to catch the other plane. No refunds and lack of communication

Late. Lack of updates. Rude hostesses. Terrible food. Lack of headphones.

Negative. Food was awful, seat broken, flight was late, baggage lost and damaged

The flight was long but everything went well. Crew was helpful and very attentive. Food was good and the entertainment options were many.

My long-haul flight experience with this airline was not very pleasant. Earphones were paid, and no eye mask or other amenities were provided. The meals were served in cardboard boxes with plastic cutlery. The restroom was unclean and ran out of toilet paper. However, the boarding process was smooth and well organized.

We experienced a delay of almost two hours before takeoff. For a flight of more than 10 hours, sitting on the runway for two hours is quite exhausting. The airline did nothing to attend to the passengers during that time. We were not given any courtesy drinks or snacks—only the bare minimum during the flight. The crew seemed very apologetic, but apparently they have restrictions imposed by the airline, because despite their friendliness, they provided strictly what was necessary and, of course, everything else was for sale. However, after a two-hour delay, one would expect at least complimentary beverages. In addition to this, the space between the rows of seats is inhumanely narrow. Air Europa should review this for such long flights and be a bit more considerate and humane with its customers.

I flew in business a couple of months ago, it was great, tried again in economy, it is the cramped seat I have ever been into, for an overseas flight across the atlantic it is inhumane to put passengers in such cramped space. Other than that, everything ok. Took a second flight from Madrid to London, also economy and it was roomy and perfect.

No WiFi on the plane. Crew was insensitive to my medical supplies and medicine in my carry on. If the crew was monitoring passengers putting 2 bags in overhead bins there would be room. We sat for 2 hours extra. Iberojet is horrible never again.

There was no water in one of the sinks in the executive area, which is unacceptable as we could not wash our hands after using the restroom

Like I said the experience was mediocre. Nothing special about this airline.

This flight was delayed by more than an hour. The seats are uncomfortable ans do not recline properly. I prepurchased a wifi pass, but wifi was not working on this flight at all. The food was bland.

Food situation was bad. Also movie choices when compared to other airlines was terrible. Seats very narrow. My tv didn’t work.

I was not allowed to cancel the flight, customer service is atrocious

The flight from Madrid to Boston was awful. Without prior warning, I was seated in the row in front of an exit row where my seat did not recline. The person in front of me reclined, reducing my already tiny space further. This was the WORST flight I've ever had.

Without any prior warning, I was seated in a row just in front of an exit row (27F), and I had no idea that my seat would not recline. However, the person in front of me did recline her seat, reducing my space. And because I could't recline to regain some space, it was my WORST flight ever.

Terrible boarding procedures in Madrid. The airplane barely has any legroom and I am 68 inches.

Worst flight I ever experienced, what was supposed to a 7 hour flight ended being 13 hours on a plane with no ac and the worst cabin I have ever seen. Never again.

Flight was fine - however my husband's checked in case was damaged, and mine still has not arrived

Bad weather Excelent pilot Spoke British 😆on time seats small ad expected in a discount airline

the seats were bad and uncomfortable and the food was not tasty.

Bad experience. The seat room are very tight. The food is not good and the breakfast has no hot drink.

The food on the flight was of marginal quality. Small bits of chicken, instant mashed potatoes and some carrots. The rolls were very dry, nearly inedible. The seats were quite small and didn’t allow for any shifting of position during the flight. There was limited leg room.0

Good plane, excellent food, crew and entertainment. Seats in business could use an upgrade

Water in bottle and a piece of chocolate were given. We did have movies to watch.

Too tight connection. Lufthansa staff pulled 12 of us out of passport control that had tight connections and took us about 1/3 mile AWAY from our gates and put us in another slow, long line. Needless to say all of us missed our flights and the Customer “Service” staff was rude and not helpful at all. Was rebooked from a direct flight to one w a 6hr layover. Asked about an other option that was on my app and was told to book it myself online (which would be $300 extra pp!!). Got rebooked again w a tight connection which was also missed. Rebooked into middle seats that didn’t recline for 9 hr flight!! No compensation (and we paid for seats!) Ended up taking 26hrs to get home from Europe to North Carolina! No longer a fan of Lufthansa—2nd time having these kind of issues w them!

Good but I don’t received my bags yet is been 5days still no update

The food on this flight was better than what we had getting to Rome. The flight was comfortable and the staff was great. One of the staff members was a stickler about the blankets in the aisle, which I get, but still. Overall, great flight and will fly with them again!

The crew were excellent, smiling and kind. The seats were good for economy though my seat back got a bit sticky from getting out of the reclining position. The food was good for a Kosher meal, better than usual. Entertainment was okay, but there was no Wi-fi available the entire flight. Overall the flight was fine for an overnight flight. The flight attendant in my section was absolutely delightful.

Fortunately the departure was delayed as I had a tight connection and the incoming flight was delayed. The departure delay helped me to make my connection. Thankfully, my luggage also could be transferred in the same time. The aircraft had to be changed and the power outlet in my seat didn’t work. Again luckily as the flight was not full, I could move to a different seat where the power outlet was working.

The legroom was lacking and the entertainment system lacked adequate selection of older films. Modern films are generally not very good.

No food, no entertainment, but that's normal for short-haul flight.

The flight attendants were wonderful - one man put my carry on in the bin for me. Very attentive service. Loved the blanket and pillow waiting for me in economy. Food was excellent which is a surprise given the reputation of any airline food. Wine was fine with the meals. Delighted with the new movies - flight went by very quickly. I would definitely fly Lufthansa again.

Everything was great…Flight Attendants were specially friendly and helpful.

Everything you need to know for your flight to South America

Cabin class types available on flights to Frankfurt am Main

Cabin classes available on flights to Frankfurt am Main. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.