VVI

446€ Find Cheap Flights from Frankfurt am Main to Santa Cruz de la Sierra – Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Cheapest return flight
931 €
Typical prices: 1.123 €-1.483 €
Multiple Airlines
Tue 6.2.Thu 15.2.
FRA - VVI • 2 stops
Cheapest one-way flight
446 €
Typical prices: 583 €-778 €
Multiple Airlines
Fri 23.2.
HHN - VVI • 2 stops
Direct flights
There are currently no direct flights between Frankfurt am Main and Santa Cruz de la Sierra. You'll need to take a connecting flight to reach the destination.
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Top routes
Cheapest • 11% average savings
Most popular
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When to book
in advance
Our data shows that travellers who book at least 25 weeks in advance save around 20% compared to booking last minute.
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When to travel
Cheapest • 17% price drop
Most popular
Good to know
+1
Good to know
+1
Top stopover airports
Cheapest • Avg 1.084 € (return)
Shortest trip • 17h 36m (one-way)
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We hope you enjoy your trip to Santa Cruz de la Sierra!
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Booking Insights
Flight Deals

Cheap Flights from Frankfurt am Main to Santa Cruz de la Sierra

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent return flight deals from Frankfurt am Main to Santa Cruz de la Sierra

Sat, 6. Feb - Mon, 15. Feb
Multiple Airlines Logo
18:55 - 2:40FRA  Frankfurt am Main-VVI Santa Cruz de la Sierra Viru Viru Intl
36h 45m2 stops Madrid Barajas Bogotá El Dorado
Multiple Airlines Logo
3:45 - 9:45VVI  Santa Cruz de la Sierra Viru Viru Intl-FRA Frankfurt am Main
25h 00m2 stops Bogotá El Dorado Madrid Barajas
931 €Multiple Airlines
Tue, 29. Sep - Wed, 28. Oct
Multiple Airlines Logo
12:10 - 22:44FRA  Frankfurt am Main-VVI Santa Cruz de la Sierra Viru Viru Intl
40h 34m2 stops Paris Charles de Gaulle Panama City Tocumen Intl
Multiple Airlines Logo
1:12 - 7:50VVI  Santa Cruz de la Sierra Viru Viru Intl-FRA Frankfurt am Main
49h 38m2 stops Panama City Tocumen Intl Atlanta Hartsfield-Jackson
965 €Multiple Airlines
Mon, 12. Oct - Mon, 2. Nov
Multiple Airlines Logo
7:00 - 3:38FRA  Frankfurt am Main-VVI Santa Cruz de la Sierra Viru Viru Intl
26h 38m2 stops Amsterdam Schiphol Panama City Tocumen Intl
Multiple Airlines Logo
11:49 - 22:05VVI  Santa Cruz de la Sierra Viru Viru Intl-FRA Frankfurt am Main
29h 16m2 stops Panama City Tocumen Intl Paris Charles de Gaulle
968 €Multiple Airlines
Sat, 6. Feb - Mon, 15. Feb
Multiple Airlines Logo
13:40 - 2:40FRA  Frankfurt am Main-VVI Santa Cruz de la Sierra Viru Viru Intl
42h 00m2 stops Madrid Barajas Bogotá El Dorado
Multiple Airlines Logo
3:45 - 13:00VVI  Santa Cruz de la Sierra Viru Viru Intl-FRA Frankfurt am Main
28h 15m3 stops Bogotá El Dorado Madrid Barajas Munich Franz Josef Strauss
978 €Multiple Airlines
Fri, 13. Nov - Sat, 5. Dec
Air Europa Logo
18:55 - 9:25FRA  Frankfurt am Main-VVI Santa Cruz de la Sierra Viru Viru Intl
19h 30m1 stop Madrid Barajas
Air Europa Logo
13:30 - 9:45VVI  Santa Cruz de la Sierra Viru Viru Intl-FRA Frankfurt am Main
15h 15m1 stop Madrid Barajas
1.120 €Air Europa
Mon, 26. Oct - Tue, 10. Nov
Air Europa Logo
18:55 - 5:55FRA  Frankfurt am Main-VVI Santa Cruz de la Sierra Viru Viru Intl
16h 00m1 stop Madrid Barajas
Air Europa Logo
13:30 - 9:45VVI  Santa Cruz de la Sierra Viru Viru Intl-FRA Frankfurt am Main
15h 15m1 stop Madrid Barajas
1.264 €Air Europa
Mon, 5. Oct - Tue, 20. Oct
Air Europa Logo
10:55 - 4:50FRA  Frankfurt am Main-VVI Santa Cruz de la Sierra Viru Viru Intl
23h 55m1 stop Madrid Barajas
Air Europa Logo
12:20 - 17:55VVI  Santa Cruz de la Sierra Viru Viru Intl-FRA Frankfurt am Main
23h 35m1 stop Madrid Barajas
1.292 €Air Europa
Thu, 12. Nov - Tue, 8. Dec
Iberia Logo
12:10 - 19:45FRA  Frankfurt am Main-VVI Santa Cruz de la Sierra Viru Viru Intl
36h 35m1 stop Madrid Barajas
Iberia Logo
20:30 - 22:35VVI  Santa Cruz de la Sierra Viru Viru Intl-FRA Frankfurt am Main
21h 05m1 stop Madrid Barajas
1.491 €Iberia
Wed, 11. Nov - Tue, 8. Dec
Iberia Logo
6:30 - 19:45FRA  Frankfurt am Main-VVI Santa Cruz de la Sierra Viru Viru Intl
18h 15m1 stop Madrid Barajas
Iberia Logo
20:30 - 6:50VVI  Santa Cruz de la Sierra Viru Viru Intl-FRA Frankfurt am Main
29h 20m2 stops Madrid Barajas Doha Hamad Intl
1.614 €Iberia
Sat, 14. Nov - Sun, 13. Dec
Iberia Logo
12:10 - 19:45FRA  Frankfurt am Main-VVI Santa Cruz de la Sierra Viru Viru Intl
36h 35m1 stop Madrid Barajas
Iberia Logo
20:30 - 22:35VVI  Santa Cruz de la Sierra Viru Viru Intl-FRA Frankfurt am Main
21h 05m1 stop Madrid Barajas
1.619 €Iberia
Booking Insights

Price, demand, and travel trends for Frankfurt am Main to Santa Cruz de la Sierra flights

Use KAYAK data on prices, travel dates, airlines, and seasonal trends to compare options and book flights from Frankfurt am Main to Santa Cruz de la Sierra with more confidence.

What's the cheapest day of the week to fly from Frankfurt am Main to Santa Cruz de la Sierra?

Monday is the cheapest day of the week to fly from Frankfurt am Main to Santa Cruz de la Sierra and is 5% cheaper than the average day. Tuesday is the most expensive day with flight prices 15% higher than average. Based on deals found by KAYAK users in the last 12 months.

What is the cheapest month to fly from Frankfurt am Main to Santa Cruz de la Sierra?

  • May and September are the cheapest months to fly from Frankfurt am Main to Santa Cruz de la Sierra at 1.046 € return.
  • December (1.615 €) and November (1.301 €) are the most expensive months.
  • The price difference between flying in the cheapest and most expensive months is 54% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are prices from Frankfurt am Main to Santa Cruz de la Sierra the cheapest?

Flights from Frankfurt am Main to Santa Cruz de la Sierra are cheapest 25 weeks before departure. Booking in this window typically costs about 20% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Key details for Frankfurt am Main to Santa Cruz de la Sierra flights

Low season

October

Cheapest flight

446 €
Best time to beat the crowds (7% less expensive on average)
Most popular time to fly and prices are also 2% lower on average.
Flights from Frankfurt-Hahn Airport to Santa Cruz de la Sierra

When to book flights from Frankfurt am Main to Santa Cruz de la Sierra

Are your dates flexible? Find out the best times to travel from Frankfurt am Main to Santa Cruz de la Sierra based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated return price

Your Frankfurt am Main to Santa Cruz de la Sierra flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines, and booking questions.

  • Which airports can I use when flying from Frankfurt am Main to Santa Cruz de la Sierra?

    Flights from Frankfurt am Main to Santa Cruz de la Sierra may depart from several airports in Frankfurt am Main area, including Frankfurt am Main (FRA) and Frankfurt-Hahn (HHN). Flights usually arrive at Santa Cruz de la Sierra Viru Viru Intl (VVI).

  • Which cabin classes can I book on flights from Frankfurt am Main to Santa Cruz de la Sierra?

    Two cabin classes are available on flights from Frankfurt am Main to Santa Cruz de la Sierra:

    • Economy class
    • Premium Economy Class

  • Which airports do connecting flights from Frankfurt am Main to Santa Cruz de la Sierra pass through?

    One-stop flights from Frankfurt am Main to Santa Cruz de la Sierra most commonly connect through:

    • Madrid Barajas (MAD) – 50% of one-stop connections
    • Sao Paulo Guarulhos Intl (GRU) – 41% of one-stop connections
    • Buenos Aires Ministro Pistarini (EZE) – 7% of one-stop connections
    • Bogotá El Dorado (BOG) – 2% of one-stop connections

    Madrid Barajas (MAD) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from Frankfurt am Main to Santa Cruz de la Sierra?

    Yes. Being flexible with your travel dates can save you up to 17% on the Frankfurt am Main to Santa Cruz de la Sierra route. Monday is the cheapest departure day at 1.209 € return on average, while Tuesday is the most expensive at 1.456 €, a difference of 247 €. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How expensive are last-minute Frankfurt am Main to Santa Cruz de la Sierra flights?

    Last-minute fares on this route (booked within 2 weeks of departure) run 12% above the route average of 1.266 €. Book 25 weeks before departure for the lowest fares.

  • How long is a flight from Frankfurt am Main to Santa Cruz de la Sierra?

    A direct flight from Frankfurt am Main to Santa Cruz de la Sierra takes 0h 00m, covering 16.523 km.

  • Do I need a passport to fly from Frankfurt am Main to Santa Cruz de la Sierra?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • Have flight prices from Frankfurt am Main to Santa Cruz de la Sierra changed much recently?

    Yes. Based on fares seen in the past 5 days, return flight prices on this route showed a wide range, from about 931 € to 6.150 €. That means the highest observed fare was about 7x higher than the lowest one.

  • How are flight prices from Frankfurt am Main to Santa Cruz de la Sierra looking right now?

    One-way fares from Frankfurt am Main to Santa Cruz de la Sierra are currently in line with typical prices for this route. Average one-way fares are about 669 €.

  • How much time can I save by choosing a different stopover airport from Frankfurt am Main to Santa Cruz de la Sierra?

    Flying via Madrid Barajas (MAD) gives the shortest average 1-stop total travel time of 17h 36m, compared to 21h 08m via Sao Paulo Guarulhos Intl (GRU) and 24h 03m via Buenos Aires Ministro Pistarini (EZE).

  • What is the time difference between Frankfurt am Main and Santa Cruz de la Sierra?

    Santa Cruz de la Sierra is 6 hours behind Frankfurt am Main (Bolivia Time vs Central European Time). Plan for the time shift when scheduling connections or first-day activities.

  • How much should I expect to pay for a Frankfurt am Main to Santa Cruz de la Sierra flight?

    Return flights from Frankfurt am Main to Santa Cruz de la Sierra range from 1.123 € to 1.483 €, with an average of 1.266 € over the past 12 months. Anything below 1.123 € counts as a good deal.

Your guide to booking Frankfurt am Main to Santa Cruz de la Sierra flights

Get tips on when to book, when to fly, and what to know before your trip.
  • If your dates are flexible, aim for a Monday departure instead of Tuesday. On this route, Monday flights average 1.209 € – about 247 € less than Tuesday (17% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 25 weeks before you fly. On this route, that window historically saves about 20% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Frankfurt am Main to Santa Cruz de la Sierra trip for May. Fares historically average 1.046 € return in that month – typically 569 € less than the most expensive month, which is December (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Santa Cruz de la Sierra Viru Viru Intl Airport.
    - Sun Hotel

More options for your flight from Frankfurt am Main to Santa Cruz de la Sierra

Complete your trip to Santa Cruz de la Sierra with a hotel stay or car hire