328€ Find Cheap Flights from South America to Frankfurt am Main – Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to Frankfurt am Main departing on 13.10.. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from South America to Frankfurt am Main

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for return flights from South America to Frankfurt am Main that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent return flight deals from South America to Frankfurt am Main

Thu, 5. Nov - Tue, 24. Nov
TAP AIR PORTUGAL Logo
16:20 - 12:30
GRU
-
FRA
16h 10m
1 stop
TAP AIR PORTUGAL Logo
6:00 - 21:40
FRA
-
GRU
19h 40m
2 stops
747 €TAP AIR PORTUGAL
Tue, 3. Nov - Tue, 24. Nov
TAP AIR PORTUGAL Logo
23:10 - 22:40
GRU
-
FRA
19h 30m
2 stops
TAP AIR PORTUGAL Logo
6:00 - 21:40
FRA
-
GRU
19h 40m
2 stops
747 €TAP AIR PORTUGAL
Sat, 8. Aug - Sat, 29. Aug
Multiple Airlines Logo
21:45 - 9:35
GRU
-
FRA
30h 50m
1 stop
Multiple Airlines Logo
18:40 - 19:50
FRA
-
GRU
30h 10m
1 stop
750 €Multiple Airlines
Sat, 8. Aug - Mon, 24. Aug
Multiple Airlines Logo
21:45 - 9:35
GRU
-
FRA
30h 50m
1 stop
Multiple Airlines Logo
14:15 - 19:50
FRA
-
GRU
34h 35m
1 stop
750 €Multiple Airlines
Tue, 11. Aug - Fri, 21. Aug
LATAM Airlines Logo
23:40 - 16:25
GRU
-
FRA
11h 45mdirect
LATAM Airlines Logo
6:30 - 20:20
FRA
-
GRU
18h 50m
1 stop
753 €LATAM Airlines
Mon, 10. Aug - Fri, 21. Aug
LATAM Airlines Logo
23:40 - 16:25
GRU
-
FRA
11h 45mdirect
LATAM Airlines Logo
6:30 - 22:25
FRA
-
GRU
20h 55m
2 stops
756 €LATAM Airlines
Tue, 20. Oct - Mon, 30. Nov
ITA Airways Logo
14:15 - 10:50
GRU
-
FRA
15h 35m
1 stop
ITA Airways Logo
7:15 - 18:40
FRA
-
GRU
15h 25m
1 stop
758 €ITA Airways
Thu, 5. Nov - Mon, 9. Nov
Air Europa Logo
15:05 - 17:55
GRU
-
FRA
22h 50m
1 stop
Air Europa Logo
19:05 - 6:30
FRA
-
GRU
15h 25m
1 stop
767 €Air Europa
Tue, 27. Oct - Thu, 5. Nov
Air Europa Logo
15:05 - 9:45
GRU
-
FRA
14h 40m
1 stop
Air Europa Logo
19:05 - 6:30
FRA
-
GRU
15h 25m
1 stop
767 €Air Europa
Sun, 1. Nov - Fri, 27. Nov
ITA Airways Logo
15:45 - 10:40
GRU
-
FRA
14h 55m
1 stop
ITA Airways Logo
7:15 - 18:40
FRA
-
GRU
15h 25m
1 stop
771 €ITA Airways
Useful Info

Good to know - Cheap tickets from South America to Frankfurt am Main

Cheapest flight

328 €
Flight from Santiago to Frankfurt am Main

FAQs for booking flights from South America to Frankfurt am Main

  • How does KAYAK find such low prices on flights from South America to Frankfurt am Main?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South America to Frankfurt am Main.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South America to Frankfurt am Main?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Frankfurt am Main from South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from South America to Frankfurt am Main?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional return ticket. You could then fly to Frankfurt am Main with an airline and back to South America with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South America to Frankfurt am Main?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Frankfurt am Main from South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines flying from South America to Frankfurt am Main

 
Need help choosing which airline to fly with from South America to Frankfurt am Main? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7,5
Air FranceOverall score based on 1629 reviews
8,2Crew
7,5Boarding
7,0Food
7,4Comfort
7,0Entertainment
Airline reviews

Seats! The eternal problem in economy. They are like stones!!

6,0 GoodJuan G, Jun 2026
IAD - CDG
Read more Air France reviews

Seats! The eternal problem in economy. They are like stones!!

The plane's pilots, including the captain himself, thanked me for the flight. I know it's just marketing, but it was really nice to see these people. It's a great idea. Airplane food is never "good," but the entire crew and flight organization were top-notch. I really liked Delta, and I think I've traveled all over the world, and that was something new for me. Maybe even the old planes, the B767, but next time I have a choice, Delta will be my first choice. Thank you, a satisfied passenger :)

Much better than the major US Carriers especially in Biz Class.

The male attended that served are section was a snob. He did not answer my call light when my wine spilled all over the floor. I did not push it again or drew his attention to it. He just ignored the call light when he came to give us our meal, serving the people behind us first. I did not push it again or drew his attention to it to see his reaction. It was so obvious that he was ignoring us. We were in premium economy!

There was 2 hours delay before boarding and 2 hours delay after boarding while waiting in the plane

They lost my lauggage and I STILL HAVE NOT RECEIVED IT. NO ONE IS HELPING! PLEASE HELP FIND MY LOST LAUGGAGE

They again did not offer any functioning WiFi in the transatlantic crossing.

Flight was late over a hour just like the first one. WiFi was down.

Did not find the wheelchair that supposed to assist and went to a long queue for transit security chk which was very slow and boarding desk wanted to close counter although that they knew that I am minutes away because of their mistake of not providing the wheelchair.

worst experience ever i choose my seat in advance and also have my seat selected in my boarding and the they told me that my seat has been changed without notify me

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

Horrible the worst airlines I have ever flown. Cancelled flight with no choices and when contacted them they were not helpful

It’s a delta flight operated by LATAM. The whole ticket sale is a mess, delta changed my flight but didn’t update it in LATAM system, I couldn’t get my boarding pass, it took me hours to resolve this issue with delta. I had to change my travel plan. No apology from Delta even though it’s their fault.

Delta has an outstanding service. They are courteous and punctual most of the time. The flight departed a half hour late but we arrived 15 minutes early.

Plane never left the ground. Mech issues - entire trip was rerouted through united.

The boading process was fine. Had to wait for bus from tarmac to terminal. Had to go through 2 or 3 security checkpoints in Lima to make next connecting flight.

Check-in was a total disaster, almos a full hour in the line

It was confusing because I got a notification that my gate was changed when in reality it wasn’t

Check in of my luggage which needed to be paid for was excellent. Thanks to Nora

There are often trade-offs involved with flying cheaper airlines. With Air Europa, their crowd control is terrible--the line at check-in in Madrid was absolutely hideous 3 hours before departure. These 787 "Dreamliners" are cheaply-made and uncomfortable. And disembarking at JFK was horrid...it was 11 p.m., yet we were force to deal with those off-site shuttle buses, presumably because Air Europa doesn't want to pay what it costs for an actual gate. But as usual, the worst aspect of Air Europa flights are tones fellow passengers: unruly and oblivious to such concepts as personal space. The crew was, on the other hand, lovely.

I flew in business a couple of months ago, it was great, tried again in economy, it is the cramped seat I have ever been into, for an overseas flight across the atlantic it is inhumane to put passengers in such cramped space. Other than that, everything ok. Took a second flight from Madrid to London, also economy and it was roomy and perfect.

Food situation was bad. Also movie choices when compared to other airlines was terrible. Seats very narrow. My tv didn’t work.

12 hours flight. Only one meal, not enough food. At the galley only water during the flight. Lavatories not clean. Headsets at extra cost.

Need to pay for a cup of water. No food. Need to pay for headsets.

They should at least offer water like other airlines, which seems like a humanitarian gesture to me

Well. It is a no frills airline. Annoying is that even for the long-haul everything has to be paid for separately. Once you add up the extras the flight is getting to expensive. Then one might as well fly with a legacy carrier which provides far better comfort. Changing flight at MAD airport is a nightmare. The worst airport in the world. Poor signposting, poor passport control, poor security check and long queues. I had 2h transfer time and spend in queues almost 1.5h

Boarding, crew and flight were very smooth and efficient. It was a bit difficult to understand the announcements on board, but it is a minor thing. What was quite bad was the very long time it took to retrieve the luggage at the Frankfurt airport.

Onboarding process and crew was excellent and efficient, Information display was great. Keep on the good work and same standard. Nothing to change.

Flights from MADRID to CARACAS and back Seats on the plane were too uncomfortable for a 9 hour trip, especially when the flight was completely full. Crew treated passengers as if we were cattle. Desperate rush to get food served so they could enjoy First class food at the back of the plane... I went twice to the back of the plane (no one answered the flight attendant button) to ask for coffee and was met with a very abrupt response... 'YOU HAVE TO PAY FOR IT'. The only thing staff could think of saying to me was 'la mascarilla senior!'.... In a way I do not blame Air Europa for getting away with this lamentable service, they are one of only two carriers flying between Spain and Venezuela so do not have any competition... I do not think they would dare offer the same service on a flight from London to Los Angeles!

Couldn’t get boarding passes online, delayed an hour, and smallest amount of space on board I’ve ever encountered for such a long flight.

It’s got the tightest seats of any airline - my knees were smashed for 3 hours - absolutely awful.

My flight being automatically moved messed up my travel plans, and I had to quickly find an alternative mode of transportation. I couldn’t get a refund from any of the companies involved. Kayak, Ibiza, or Vueling. I am still unsure of how to settle my concern.

The flight was safe, confortable and convenient. Thank you. I hope to come back soon!

Terrible. Boarding was a mess. We were assigned middle seats and separate just to induce us to pay for better seats. Cabin luggage was checked in while space remained on the overboard lockers. I think they don't really care about the customer.

A friendlier and more helpful crew would have been much better.

Yeah you have time and can sit around for a while to be okay for you but if you planned on getting connected flights I recommend not to fly with this Airline it's best they for flying out of the country

it would good to have at least something to drink...

Never made this flight it was unconfirmed by Iberia according to American Airlines This trip was a total nightmare, got to the airport in Wed March 8th after confirming all flights, only to be told by American Airlines that we are not confirmed on the flight. We met a pretty rude and unhelpful AA check in agent by the name of Ali. American said it was not their problem, contact Kayak/Chatdeal and sort out your issue.Chatdeal said all flights were confirmed and it is the airlines fault. So it went, we were kicked between American, Kayak and Iberia spending hrs on the phone- all said it is not their fault.Spent 9 hrs in the airport on Wed 15th trying to sort out. Luckily, we met a really nice AA agent Shawnna G who went way beyond the call of.duty to help us out. We were put the next day on Thurs 16th from DfW to San Paulo Brazil the onto Madrid!! Imagine that..10000 miles and 20hrs of travelling to get to Madrid from Dallas!! Our trip took 3 days to get there ..Wed 8th Thurs 9th and Fri 10th.Got there on Sat 11th, so lost 2 days of our vacation and a lot of emotional and physical stress on our 2 kids travelling with us.

This trip was a total nightmare, got to the airport in Wed March 8th after confirming all flights, only to be told by American Airlines that we are not confirmed on the flight. We met a pretty rude and unhelpful AA check in agent by the name of Ali. American said it was not their problem, contact Kayak/Chatdeal and sort out your issue.Chatdeal said all flights were confirmed and it is the airlines fault. So it went, we were kicked between American, Kayak and Iberia spending hrs on the phone- all said it is not their fault.Spent 9 hrs in the airport on Wed 15th trying to sort out. Luckily, we met a really nice AA agent Shawnna G who went way beyond the call of.duty to help us out. We were put the next day on Thurs 16th from DfW to San Paulo Brazil the onto Madrid!! Imagine that..10000 miles and 20hrs of travelling to get to Madrid from Dallas!! Our trip took 3 days to get there ..Wed 8th Thurs 9th and Fri 10th.Got there on Sat 11th, so lost 2 days of our vacation and a lot of emotional and physical stress on our 2 kids travelling with us.

Very efficient and excellent service. Nice amenities and beautiful plane. Elevated meals. Boarding could have been more organized. We missed our connecting flight due to EU entry but Lufthansa was extremely quick to rebook us.

Aircraft had fairly roomy seats on economy. Food was good (beef dinner).

Broken seat did not recline fully, broken footrest, no air vents, no electricity for charging devices, outlets for headphones or isb did not work. Rude crew. Horrible experience. Would never fly Lufthansa again

They did not serve my special meal request after departure of airplane

It was a very smooth and on time flight experience. The crew was really friendly and polite. We were well informed about the flight, etc.

Lufthansa was horrible for disabled folks. My wife had hell of a time making it to the flight in Frankfurt. The airlines is not at all caring to the disabled. If that were in USA I would have sued the airline for not meeting the disability Act clause. No way we are going to go in Lufthansa again. Hari S Doss

The Discover flight from TPA to FRA was exceptionally unprofessional and incompetent in organization. First the entertainment system was completely nonfunctional for the entire plane and no competent IT support to fix. Than they could not serve any coffee or tea because they ran out of water - reflecting the exceptionally incompetent management at Discovery and most embarrassing for Lufthansa and a German airline, more like a third world country. The food was mediocre at best and minimalistic for Discover, particularly with the much higher standards at Lufthansa.

Lufthansa's Miami International counter folks are very strict on carry-on weight. Can't be greater than 8 kg otherwise they force you to check it for a fee. Bags came out at baggage claim as soon as we arrived to that location (it is a far walk from arrival gate to bag pickup). We do travel with Lufthansa domestically and enjoy every trip.

My husband had a surgery sometime ago but had to stand for more than 2 hrs in the line just to check in, drop baggage and pay for excess. The staff is toooo slow leading to long ques. This made our journey very stressful to begin with. Had to literally run at the airport through the security check and to the gate in spite of reaching 3 hrs before the flight. it was almost time to board by the time we finished checking in our bags

Very good crew, enough space between seats, very good food! Captain of this plane was incredible, quietly and safe fly!

Everything you need to know for your flight to Frankfurt am Main

Cabin class types available on flights to South America

Cabin classes available on flights to Frankfurt am Main. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.