385€ Find Cheap Flights from Düsseldorf Airport to South America – Compare and Save

1 adult
1 adult, Economy, 0 bags

Save 23% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Flight Deals
Booking Insights
Flight Deals

Best South America Flight Deals from Duesseldorf Intl

Cheapest return prices found by our users on KAYAK in the last 5 days
Sao Paulo
Sao Paulo1 stop659 €
Bogotá
Bogotá1 stop655 €
Lima
Lima2 stops835 €
Rio de Janeiro
Rio de Janeiro2 stops737 €
Santiago
Santiago2 stops844 €
Quito
Quito1 stop841 €
Salvador
Salvador1 stop676 €
Recife
Recife2 stops676 €
Asuncion
Asuncion1 stop913 €
Cartagena
Cartagena2 stops755 €
Montevideo
Montevideo1 stop829 €
Fortaleza
Fortaleza1 stop722 €
Cali
Cali1 stop904 €
Cusco
Cusco2 stops890 €
Santa Marta
Santa Marta2 stops1.129 €
Guayaquil
Guayaquil2 stops953 €
Santa Cruz de la Sierra
Santa Cruz de la Sierra1 stop1.117 €
Caracas
Caracas1 stop717 €
Sao Paulo
Sao Paulo1 stop659 €
Bogotá
Bogotá1 stop655 €
Lima
Lima2 stops835 €
Rio de Janeiro
Rio de Janeiro2 stops737 €
Santiago
Santiago2 stops844 €
Quito
Quito1 stop841 €
Salvador
Salvador1 stop676 €
Recife
Recife2 stops676 €
Asuncion
Asuncion1 stop913 €
Cartagena
Cartagena2 stops755 €
Montevideo
Montevideo1 stop829 €
Fortaleza
Fortaleza1 stop722 €
Cali
Cali1 stop904 €
Cusco
Cusco2 stops890 €
Santa Marta
Santa Marta2 stops1.129 €
Guayaquil
Guayaquil2 stops953 €
Santa Cruz de la Sierra
Santa Cruz de la Sierra1 stop1.117 €
Caracas
Caracas1 stop717 €
Booking Insights

KAYAK's insights & trends for Duesseldorf Intl to South America flights

Get data-powered insights and trends into flights from Duesseldorf Intl to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Duesseldorf Intl Airport to South America?

The cheapest month for flights from Duesseldorf Intl Airport to South America is February, when tickets cost 906 € (return) on average. On the other hand, the most expensive months are December and August, when the average cost of return tickets is 1.344 € and 1.308 € respectively.

How far in advance should I book a flight from Duesseldorf Intl Airport to South America?

To get a below-average price on a flight from Duesseldorf Intl Airport to South America, you should book around 2 weeks before departure, which saves you about 18% compared to booking last-minute. For the absolute cheapest price, our data suggests you should book 18 weeks before departure.

Good to know - Cheap tickets from Düsseldorf Airport to South America

Low season

June

Cheapest flight

385 €
Best time to beat the crowds (1% less expensive on average)
Most popular time to fly (26% more expensive on average)
Flight from Düsseldorf to Buenos Aires

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Düsseldorf Airport to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Düsseldorf Airport to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Düsseldorf Airport to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Düsseldorf Airport to South America is likely to change within 7 days, so travellers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Düsseldorf Airport to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional return ticket. You could then fly from Düsseldorf Airport to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Düsseldorf Airport to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Düsseldorf Airport to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines flying from Duesseldorf Intl to South America

 
Need help choosing which airline to fly with from Duesseldorf Intl to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7,8
KLMOverall score based on 1578 reviews
7,7Comfort
7,3Food
7,2Entertainment
8,4Crew
7,8Boarding
Airline reviews

It was my first KLM flight and I loved it. Thank you very much.

10,0 ExcellentAnonymous, Aug 2026
Read more KLM reviews

It was my first KLM flight and I loved it. Thank you very much.

KLM remains a quality flag carrier airline which maintains its standards whilst all their competitors are lowering theirs.

The baggage drop-off in Stuttgart is bad: after online check-in you cannot use the automated baggage drop off as indicated on the website. You can use the terminals but have to cue to 1 of three open and slowly working counters to drop the bags. took about 45 minutes wait time.

Great boarding, great short flight but no entertainment whatsoever and no wifi. Prepare to disembark by a staircase.

Flight left a few minutes late, but that's it. I wish the seats could be wider and recline more.

The baggage service at Malpensa was the worst ever. We wanted for over an hour without any information, they broke my suitcase, and the services of the local luggage services company was below any usual services level of a KLM partner.

Good experience, just i couldn’t connect me to the wifi

Was trying to change a flight but told that Canadian and local klm systems do not interact so they could not access my booking. Overall I like klm a lot but if it was important to change flights I would be very frustrated.

I travel frequently. The flight was late again... KLM should really try and be on time

Seats actually fit a human! Snack options were a bit lame but that’s ok

They lost my bag and I still have not received it

I don’t like that an equipment change caused my seat to change from 23A to 44A. The boarding was also delayed. The crew were excellent, however and very attentive. The food was not bad.

Old airplanes small seats expensive tickets, not as expected overall and not comfortable according to the price

They lost my lauggage and I STILL HAVE NOT RECEIVED IT. NO ONE IS HELPING! PLEASE HELP FIND MY LOST LAUGGAGE

I paid 3 this and dollars for two tickets. No food, minimum drink, confused service and very uncomfortable sear. There was zero difference between busy ness and tourist class. I received a pathetic apology

Old cabine without flat bed in business for a 12 hour flight is not acceptable

Everything went smoothly with Air France. There was a delay in departure which seemed to relate to the immigration services being short staffed.

Food could have been better especially the breakfast. Overall it was a good flight

I have used Air France and KLM many times it will help if they change their menu's feel like it's been the same for years!!!, Especially the breakfast. Overall the flight was good and enjoyable.

My seat was so uncomfortable, and the headrest was broken. Very very disappointing for the price I paid.

They blocked me from checking in online and they charged me lots of money

The plane was small and one felt the turbulence much more. The lines to get through immigration were insanely long.

Our steward Margarida who served us from Lisbon to Boston was absolutely fantastic! She deserves a raise. Conscientious and thorough as well as showing appropriate attention for every need.

I had a business class ticket from EWR to Madrid with a layover at LIS for 11 hours. It was obvious that I needed to pick up my luggage in Lisbon for 11 hours and check it in again when boarding the second flight to Madrid. Before buying the ticket, I called TAP customer service. Customer service assured me that I could get my luggage in Lisbon. When I arrived at Newark airport, I immediately asked to check my luggage to Lisbon. However, the TAP employee refused me, saying that I should resolve this issue upon arrival in Lisbon. She checked my luggage to Madrid. I asked the TAP employee at the gate to help me when boarding the plane, I asked the flight attendants manager on board the plane to help me. All the employees refused to help me and said that I should resolve this issue in Lisbon. It took me 4 hours to resolve this issue in Lisbon. I arrived at 11am and they didn't give me my luggage until 3pm. As a result, I was so tired after a sleepless night on the plane and 4 hours on my feet at the airport and all my plans were ruined that I couldn't fly to Madrid. It was a terrible experiance,

Comfortable but not Polaris or Delta comfort Business Class. Overall 7 out of 10

Great overall experience with TAP - would not hesitate to recommend for your next trip to or from Portugal

A bit disappointing. Our business class seats were not cleaned from previous flight. They were also missing headphones and bottled water. Dining options were not always available.

Didn't get to go because connection flight was cancelled

I have been flying internationally for most of like. My first trip with TAP- wonderful! I look forward to flying with them more frequently in the future!

Of course food only if you pay and no entertainment. As always with TAP they collected hand luggage and you must check in. This happens mostly with TAP and is not acceptable because others are having three pieces or more. TAP should be consequent and collect hand luggage only from those who have more than one piece.

Everything was on time and easy. Food in business class was great. There was no entertainment on board, though with business class you could get free internet, but so spotty it wasn't worthwhile.

They could have provided more than a premade mass produced tina sandwich for a 10 hour delay and/or had something available on oars other than potat chips once we boarded. They also could have not lost our luggage. Or barring that, at least foled a claim for us once we landed. Instead all of those things happened and they told us if we wanted to file a claim to do so online. I laid for business class for both of us. What an incredible waste of money.

Without any prior warning, I was seated in a row just in front of an exit row (27F), and I had no idea that my seat would not recline. However, the person in front of me did recline her seat, reducing my space. And because I could't recline to regain some space, it was my WORST flight ever.

I’m an Iberia fan but this time They dropped the ball. I went from ALC to MAD to LHR. Boarding in ALC was by group… to get you in a bus. Then we sat for almost an hour when most people had connections. When we landed in Madrid we did so and they put us in another bus almost like if they wanted to make people lose their connection. We made ours by the skin of our teeth but our luggage did not. And on top of this we had to listen to the pilot bragging about Iberia being punctual. To be true we made it on time to LHR but we are Still waiting for our luggage

This is where i leave an airline review. Test test test!

business class food was pretty average otherwise it was a good experience

okay, will recommend from PR to Madrid, faster turn around

I fly to BNA with BA often and this was the worst experience. Arriving in nashville, check in was 1.5 hrs long in the queue with 1 very slow girl at the desk. When more staff came they only catered to priority customers. When all priority were checked in, instead of filtering from the top of the line they took the people from the end, the people who had been queuing for 5 mins vs almost 2 hours. The flight was delayed, for no good reason other than the staff took forever to do anything. At the gate there was zero organisation, we asked the crew what the delay was and they confirmed it wasn't the plane and it was the ground team. One of the flight attendants was one of the rudest I have EVER encountered, that man clearly hated his job, and people...I wish I'd got his name. Food was disgusting, seating was cramped. I've no idea what's changed in the last year but I'm truly shocked.

All went smoothly, no problems; friendly crew. I would have appreciated a head pillow ;)

Never made this flight it was unconfirmed by Iberia according to American Airlines This trip was a total nightmare, got to the airport in Wed March 8th after confirming all flights, only to be told by American Airlines that we are not confirmed on the flight. We met a pretty rude and unhelpful AA check in agent by the name of Ali. American said it was not their problem, contact Kayak/Chatdeal and sort out your issue.Chatdeal said all flights were confirmed and it is the airlines fault. So it went, we were kicked between American, Kayak and Iberia spending hrs on the phone- all said it is not their fault.Spent 9 hrs in the airport on Wed 15th trying to sort out. Luckily, we met a really nice AA agent Shawnna G who went way beyond the call of.duty to help us out. We were put the next day on Thurs 16th from DfW to San Paulo Brazil the onto Madrid!! Imagine that..10000 miles and 20hrs of travelling to get to Madrid from Dallas!! Our trip took 3 days to get there ..Wed 8th Thurs 9th and Fri 10th.Got there on Sat 11th, so lost 2 days of our vacation and a lot of emotional and physical stress on our 2 kids travelling with us.

Loved the towel at the end. Service was frequent and perfect.

Horrible. Would not assist w hotel or new flights when Catania leg canceled

Absolutely horrible. We missed both of our connecting flights from Frankfort due to the new border control lines. Lufthansa had us running and walking around the airport trying to rebook. They were not prepared to offer us a hotel room for the night, but finally relented when I said I was done with Lufthansa, most were not so lucky. I also put put of the blame in Kayak. You need to update which connecting flights you are offering to allow for more time to deal with the mess that is border control in the EU.

Cheapflights did not forward the payment for seat assignments, and my partner and I were separated and given center (B and E) seats. Will be requesting a refund.

Connecting in Frankfurt was a nightmare! Whoever scheduled our connection in Frankfurt for 90 minutes should be fired! Passport control takes 3 hours, minimum! Avoid Frankfurt airport at all costs! Never again! The airport is 3rd world. The WORST!

It was ok no problem on flight after the ordeal with passport control. Long line and nasty officers not very helpful.

Good flight but there was no entertainment. I wouldn’t have complained but you asked.

roomiest flight in economy I've taken in years. Excellent experience!

I was disappointed that paying nearly $5000 more for business class for two didn’t really get me any more than a larger seat which as the last row in cabin reclined only mildly and the foot supports were of minimal help and left no room under seat ahead for carton bag. Second, our checked luggage was lost and took us two long days and we’ll after midnight each of them and multiple calls and 30 euro trip to airport in person to finally get them. Would you do this again?

Boarding process was late Could do a pre-announcement of flight status.

More options for your flight to South America

Complete your trip to South America with a hotel stay or car hire