484€ Find Cheap Flights from Panama to Frankfurt Airport – Compare and Save

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Cheap Flights from Panama to Frankfurt

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent return flight deals from Panama to Frankfurt

Sun, 20. Sep - Tue, 17. Aug
Air France Logo
22:15 - 22:05PTY  Panama City Tocumen Intl-FRA Frankfurt am Main
16h 50m1 stop Paris Charles de Gaulle
Air France Logo
7:05 - 19:45FRA  Frankfurt am Main-PTY Panama City Tocumen Intl
19h 40m1 stop Paris Charles de Gaulle
621 €Air France
Sun, 20. Sep - Tue, 17. Aug
Air France Logo
22:15 - 22:05PTY  Panama City Tocumen Intl-FRA Frankfurt am Main
16h 50m1 stop Paris Charles de Gaulle
Air France Logo
7:05 - 19:45FRA  Frankfurt am Main-PTY Panama City Tocumen Intl
19h 40m1 stop Paris Charles de Gaulle
638 €Air France
Sun, 20. Sep - Tue, 17. Aug
Multiple Airlines Logo
22:15 - 22:05PTY  Panama City Tocumen Intl-FRA Frankfurt am Main
16h 50m1 stop Paris Charles de Gaulle
Multiple Airlines Logo
7:00 - 19:45FRA  Frankfurt am Main-PTY Panama City Tocumen Intl
19h 45m2 stops Amsterdam Schiphol Paris Charles de Gaulle
649 €Multiple Airlines
Sat, 19. Sep - Tue, 17. Aug
Multiple Airlines Logo
21:41 - 11:05PTY  Panama City Tocumen Intl-FRA Frankfurt am Main
30h 24m2 stops Port of Spain Piarco Intl Amsterdam Schiphol
Multiple Airlines Logo
7:05 - 19:45FRA  Frankfurt am Main-PTY Panama City Tocumen Intl
19h 40m1 stop Paris Charles de Gaulle
668 €Multiple Airlines
Sat, 19. Sep - Tue, 17. Aug
KLM Logo
21:41 - 11:05PTY  Panama City Tocumen Intl-FRA Frankfurt am Main
30h 24m2 stops Port of Spain Piarco Intl Amsterdam Schiphol
KLM Logo
7:00 - 19:45FRA  Frankfurt am Main-PTY Panama City Tocumen Intl
19h 45m2 stops Amsterdam Schiphol Paris Charles de Gaulle
695 €KLM
Sun, 27. Sep - Tue, 17. Aug
KLM Logo
18:50 - 9:35PTY  Panama City Tocumen Intl-FRA Frankfurt am Main
31h 45m1 stop Amsterdam Schiphol
KLM Logo
10:15 - 19:45FRA  Frankfurt am Main-PTY Panama City Tocumen Intl
16h 30m2 stops Amsterdam Schiphol Paris Charles de Gaulle
726 €KLM
Thu, 22. Oct - Tue, 27. Oct
Air Europa Logo
20:25 - 9:45PTY  Panama City Tocumen Intl-FRA Frankfurt am Main
30h 20m1 stop Madrid Barajas
Air Europa Logo
10:45 - 19:45FRA  Frankfurt am Main-PTY Panama City Tocumen Intl
15h 00m1 stop Madrid Barajas
762 €Air Europa
Mon, 19. Oct - Wed, 18. Nov
Air Europa Logo
20:25 - 9:45PTY  Panama City Tocumen Intl-FRA Frankfurt am Main
30h 20m1 stop Madrid Barajas
Air Europa Logo
18:55 - 19:45FRA  Frankfurt am Main-PTY Panama City Tocumen Intl
30h 50m1 stop Madrid Barajas
769 €Air Europa
Sun, 7. Feb - Sat, 27. Feb
Iberia Logo
18:35 - 18:50PTY  Panama City Tocumen Intl-FRA Frankfurt am Main
18h 15m1 stop Madrid Barajas
Iberia Logo
19:35 - 17:05FRA  Frankfurt am Main-PTY Panama City Tocumen Intl
27h 30m1 stop Madrid Barajas
839 €Iberia
Thu, 4. Feb - Sat, 13. Feb
Iberia Logo
10:34 - 22:35PTY  Panama City Tocumen Intl-FRA Frankfurt am Main
30h 01m2 stops San José Juan Santamaria Intl Madrid Barajas
Iberia Logo
12:10 - 17:05FRA  Frankfurt am Main-PTY Panama City Tocumen Intl
34h 55m1 stop Madrid Barajas
882 €Iberia
Booking Insights

KAYAK's insights & trends for flights to Frankfurt

Get data-powered insights and trends into flights to Frankfurt to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest day to fly to Frankfurt am Main?

Based on KAYAK data, the cheapest day to fly to Frankfurt am Main is Monday where round-trip tickets can be as cheap as 699 €. On the other hand, the most expensive day to fly is Thursday, where round-trip prices are 717 € on average.

What is the cheapest month to fly to Frankfurt am Main Airport?

The cheapest month for flights to Frankfurt am Main Airport is November, where tickets cost 608 € on average for return flights. On the other hand, the most expensive months are July and September, where the average cost of tickets from Panama is 958 € and 935 € respectively. For one-way flights, the best month to travel is November with an average price of 309 €.

What is the cheapest time of day to fly to Frankfurt am Main Airport?

The cheapest time of day to fly to Frankfurt am Main Airport is generally in the morning, when round-trip flights cost 629 € on average. The most expensive time of day to fly to Frankfurt am Main Airport is generally at night, which is peak travel time and where the average cost of a ticket is 699 €.

How far in advance should I book a flight to Frankfurt am Main Airport?

To get a below average price, you should book around 1 week before departure. For the absolute cheapest price, our data suggests you should book 19 weeks before departure.

Good to know - Cheap tickets from Panama to Frankfurt Airport

Low season

January

Cheapest flight

484 €
Best time to beat the crowds but there is an average 8% increase in price.
Most popular time to fly and prices are also 4% lower on average.
Flight from Panama City to Frankfurt am Main

FAQs - booking Frankfurt Airport flights

  • How far is Frankfurt am Main Airport from central Frankfurt am Main?

    The distance between Frankfurt am Main Airport and the city centre of Frankfurt am Main is 12 km.

  • How does KAYAK find such low prices on flights to Frankfurt Airport?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights to Frankfurt Airport.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket to Frankfurt Airport?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Frankfurt Airport is likely to change within 7 days, so travellers know whether to wait or book now.

  • What is the Hacker Fare option on flights to Frankfurt Airport?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional return ticket. You could then fly to Frankfurt Airport with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight to Frankfurt Airport?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Frankfurt Airport up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • How many direct flights to Frankfurt am Main Airport are there each week?

    Each week there are around 2.226 direct flights from within Panama to Frankfurt am Main Airport. The most common day for departures is Sunday, with 16% of flights taking off on this day.

Top tips for finding cheap flights to Frankfurt Airport

  • Enter your preferred departure airport and travel dates into the search form above to unlock the latest Frankfurt Airport flight deals.

Reviews of the top 5 airlines flying from Panama to Frankfurt

 
Need help choosing which airline to fly with to Frankfurt? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7,8
KLMOverall score based on 1576 reviews
7,2Entertainment
7,3Food
7,8Boarding
7,7Comfort
8,4Crew
Airline reviews

The flight was excellent, the crew was super friendly. The only complaint I have is, 3 of my zipper handles were broken and there were 2 massive scratches on the back of my bag

4,0 Okayankit, Jul 2026
Read more KLM reviews

The flight was excellent, the crew was super friendly. The only complaint I have is, 3 of my zipper handles were broken and there were 2 massive scratches on the back of my bag

As always, it’s a pleasure to travel with KLM. It is one of my favorite airlines.

Couldn’t get boarding pass in SLC even with help from a redcoat, so had to find a desk in AMS to get boarding pass. Technical problems so not sure why. Very inconvenient. The KLM app is not as user friendly as most apps. Also had to wait almost an hour on the tarmac for a fuel truck, which caused us to miss a connecting bus in LUX.

There was fog in Amsterdam so many flights were delayed because of the weather. Air France knew that the flight would be delayed by two hours but still boarded the plane on time. Instead of letting the passengers wait at the gate we were crammed into the plane. It was uncomfortable. No refreshments were given. I couldn’t charge my devices onboard.

It’s chaotic at the bus stop outside of the airport because of the Uber meeting point. You need to be alert and look for the KLM bus which is not branded or labeled. Incorrect information was provided to go to gate 28, when in fact the bus was at gate 27. On the plus side the bus left early and arrived early to Ottawa.

Delay, luggage didn’t arrive. Had to go the next day to collect it

The flight was again delayed for more then 2 hours with some lousy explanation regarding the reason of the delay. Although the flight was delayed for more than 2 hours, no refreshments were offered (according to EU regulations). Last 4 flights on KLM - always at least 2 hrs late. So be prepared that you cannot plan anything with KLM.

I thought KLM was the best airline but the Lima - Amsterdam was 1 hours late, the Brussels - Amsterdam was 2.30 hours late and the Amsterdam - Lima was 30 minutes late

The food quality is poor. The staff are very friendly and accommodating. The entertainment program was limited. I experienced a delay of 30 minutes due to two issues. Passenger luggage had to be removed and there was a technical issue with the stairs not detaching from the aircraft. The pilot managed to compensate and we arrived only 15 minutes later. The luggage at Dubai airport was very slow. I waited over an hour.

Everything in general was great, but we left 30 minutes late

The seat in front of me seemed to have extra reclining, which made my seat tighter. I couldn’t see my movie properly when the other passenger was reclined. Food was OK, but there was a long period without food, considering it was a day time long flight.

The plane's pilots, including the captain himself, thanked me for the flight. I know it's just marketing, but it was really nice to see these people. It's a great idea. Airplane food is never "good," but the entire crew and flight organization were top-notch. I really liked Delta, and I think I've traveled all over the world, and that was something new for me. Maybe even the old planes, the B767, but next time I have a choice, Delta will be my first choice. Thank you, a satisfied passenger :)

Worst airlines either. First leg was delayed because of crew not available. My connection was missed so they booked me automatically the next day! But, impossible to get anyone on site, web site does not let me access my reservation anymore, confirmed by useless agents over the phone. My 2-leg trip with part in business class arriving at 4:10pm ends up in an awful 3-leg arriving at 9pm the next day with no way to even choose the seats and of course at the very end of the plane. I can understand problems arrive but the way Air France handle it is just unacceptable. You are on your own. Apparently getting you to your destination is the only thing they consider their duty. The customer experience and fatigue is none of their concern. And I have a status with them. I will reconsider my priorities when flying with Air France and encourage everyone to do the same.

3 hour delay but out of their control. App said I get vouchers but when I applied for them, they were nowhere to be found in my account

It was a great experience. The only thing I would have changed was that the bathrooms were never cleaned and they got very dirty.

Not a good one this time. The absence of internet without any information/notification ahead was really the unacceptable part. Also this new A350-900 has a serious legroom challenge for economy seats. It’s more like a medium-haul flight legroom configuration.

Boarding was a disaster being moved by Air France by bus to the plane. The plane should have been at the right gate.

Excellent apart from transport to actual plane 10 minutes from the actual gate , walking out in the tarmac in the rain and having to climb stairs to enter while holding luggage.

Good aorcraft 777 but Worst food ever Breakfast was a bû’with matonnaise… Staff was nice but invisible most of the flight

Please serve no god if you must serve dog food

We waited in the jetway for over an hour before we got on the plane.

I flew in business a couple of months ago, it was great, tried again in economy, it is the cramped seat I have ever been into, for an overseas flight across the atlantic it is inhumane to put passengers in such cramped space. Other than that, everything ok. Took a second flight from Madrid to London, also economy and it was roomy and perfect.

My luggage is lost and nowhere to be found, no response from airline

Boarding was a shitshow. Had to bus to the gate. No separate bus and boarding process for Business Class.

They should at least offer water like other airlines, which seems like a humanitarian gesture to me

Well. It is a no frills airline. Annoying is that even for the long-haul everything has to be paid for separately. Once you add up the extras the flight is getting to expensive. Then one might as well fly with a legacy carrier which provides far better comfort. Changing flight at MAD airport is a nightmare. The worst airport in the world. Poor signposting, poor passport control, poor security check and long queues. I had 2h transfer time and spend in queues almost 1.5h

Probably will never use this air line again. Rude miserable staff. Uncomfortable seats.

Very BAD crew service They ignore at all any call for service . Very rude from the check in process to all the tripularion members in the fight .

Boarding, crew and flight were very smooth and efficient. It was a bit difficult to understand the announcements on board, but it is a minor thing. What was quite bad was the very long time it took to retrieve the luggage at the Frankfurt airport.

Terrible app. Working off paper stickies for seat reservations doesn’t work anymore.

It’s got the tightest seats of any airline - my knees were smashed for 3 hours - absolutely awful.

The boarding procedure got confusing because they wanted to weigh everyone’s carry-on. Apparently mine was 3 1/2 kg over their limit. I didn’t know they had a limit. And at the check-in desk, nothing was said about this. They wanted me to check the carry-on at no charge and that would have been fine except then they told me at my connection in London I would have to go outside to baggage claim retrieve my bag, and then recheck it. In other words, they could not check it to my final destination, only to London. I told him this was unacceptable so after a few minutes of discussion, they came back and said that my bag would be OK to carry on the plane. It seems that if you have a connection then the weight is not as important. Then when I actually went to board the boarding agent said I needed a tag indicating that my bag had been weighed, even though she had just five minutes ago talked to the same person who cleared me. Lots of confusion seems like a very bad process. They need to improve this.

Boarding was odd. Gates switched and had to take a bus to the plane. Luggage got lost. Still waiting on one bag. Flight itself was very nice!

Not having to check carry on bags when plane wasn’t full. (The told us it was)

very good all round. staff, food, entertainment, punctuality all very good

A friendlier and more helpful crew would have been much better.

Yeah you have time and can sit around for a while to be okay for you but if you planned on getting connected flights I recommend not to fly with this Airline it's best they for flying out of the country

The trays weren’t wiped. They still had food from last passengers

it would good to have at least something to drink...

This trip was a total nightmare, got to the airport in Wed March 8th after confirming all flights, only to be told by American Airlines that we are not confirmed on the flight. We met a pretty rude and unhelpful AA check in agent by the name of Ali. American said it was not their problem, contact Kayak/Chatdeal and sort out your issue.Chatdeal said all flights were confirmed and it is the airlines fault. So it went, we were kicked between American, Kayak and Iberia spending hrs on the phone- all said it is not their fault.Spent 9 hrs in the airport on Wed 15th trying to sort out. Luckily, we met a really nice AA agent Shawnna G who went way beyond the call of.duty to help us out. We were put the next day on Thurs 16th from DfW to San Paulo Brazil the onto Madrid!! Imagine that..10000 miles and 20hrs of travelling to get to Madrid from Dallas!! Our trip took 3 days to get there ..Wed 8th Thurs 9th and Fri 10th.Got there on Sat 11th, so lost 2 days of our vacation and a lot of emotional and physical stress on our 2 kids travelling with us.

Crew and seats were ok. Food was just simply terrible.

The flight was fine, only issue my friend had was how small the seats were, it's a 10 hour flight so it becomes a bit of an issue when you're sort of cramped.

Based on some reviews, my expectations were low. I must say, the experience in Premium Economy was terrific. Comfortable seat, food was good and service was consistently good. I would certainly consider Condor again.

Missed connection due to no fault of our own, rude staff across the board, nearly 4 hrs in line for Condor service desk to ‘rebook’. Paid $5000 just to be lucky enough to get home next day.. will never fly with condor again.

The worst experience with an airline in my 50 years of flying.

The flight left 1.5 hours late but there was no information about the delay. My business class cabinet had two small children who cried much of the trip. Service seemed rushed.

I didn't like breakfast, I prefer plain rolls with butter.

Part of our luggage was lost and we had to wait 48 hours before receiving it. Also someone had to wait in the hotel to get it!!! Frustrating & disappointing

Condor computers constantly shut down. They had to book entire 747 off one computer. Condor does not leave enough time for their own scheduled layovers in Frankfurt. It is not possible to get through customs and to the gate on time. Both trips were a mess. Condor was so bad that they had to book half the people on Lufthansa to complete their journey. I do not recommend Condor for any reason for anyone.

We missed our connecting flight in Frankfurt due to being stuck in the passport line for two hours. Condor said they would not help us because we had a one hour layover which is enough time. When I explained that the line took two hours, they acknowledged that the line is that way but that is the airport and not them. We are now stuck in Frankfurt for two days and it has cost us $500.

Travelling to a place near Frankfurt?

Book flights to Frankfurt if you plan to visit one of these locations
Wurzburg
Koblenz
Mainz
Trier
Baden-Baden
Wiesbaden
Cochem
Fulda
Bad Kissingen
Darmstadt
Marburg
Rothenburg ob der Tauber
Aschaffenburg
Bernkastel-Kues
Rüdesheim am Rhein
Heilbronn
Pforzheim
Speyer
Kaiserslautern
Bad Homburg

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